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Buffalo Bills 2023 NFL Schedule
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Regular Season
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| Date | Opponent | Stadium | Time |
| Mon, Sep 11 | @ New York Jets | | 8:15:00 PM |
| Sun, Sep 17 | vs Las Vegas | | 1:00:00 PM |
| Sun, Sep 24 | @ Washington | | 1:00:00 PM |
| Sun, Oct 1 | vs Miami | | 1:00:00 PM |
| Sun, Oct 8 | vs Jacksonville(London) | | 9:30:00 AM |
| Sun, Oct 15 | vs New York Giants | | 8:20:00 PM |
| Sun, Oct 22 | @ New England | | 1:00:00 PM |
| Thu, Oct 26 | vs Tampa Bay | | 8:15:00 PM |
| Sun, Nov 5 | @ Cincinnati | | 8:20:00 PM |
| Mon, Nov 13 | vs Denver | | 8:15:00 PM |
| Sun, Nov 19 | vs New York Jets | | 4:25:00 PM |
| Sun, Nov 26 | @ Philadelphia | | 4:25:00 PM |
| BYE WEEK | | | |
| Sun, Dec 10 | @ Kansas City | | 4:25:00 PM |
| Sun, Dec 17 | vs Dallas | | 4:25:00 PM |
| Sat, Dec 23 | @ Los Angeles Chargers | | 8:00:00 PM |
| Sun, Dec 31 | vs New England | | 1:00:00 PM |
| Sun, Jan 7 | @ Miami | | TBD |
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