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South Carolina NFL Draft Choices
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| Year | Round | Overall | Name | Team | Position | School |
| 2023 | 2 | 51 | Cam Smith | Dolphins | CB | South Carolina |
| 2023 | 3 | 64 | Zacch Pickens | Bears | DT | South Carolina |
| 2023 | 5 | 138 | Darius Rush | Colts | CB | South Carolina |
| 2023 | 7 | 225 | Jovaughn Gwyn | Falcons | OG | South Carolina |
| 2023 | 7 | 244 | Jalen Brooks | Cowboys | WR | South Carolina |
| 2022 | 5 | 179 | Kingley Enagbare | Packers | LB | South Carolina |
| 2022 | 6 | 183 | Kevin Harris | Patriots | RB | South Carolina |
| 2022 | 7 | 227 | Nick Muse | Vikings | TE | South Carolina |
| 2021 | 1 | 8 | Jaycee Horn | Panthers | CB | South Carolina |
| 2021 | 3 | 103 | Ernest Jones | Rams | LB | South Carolina |
| 2021 | 6 | 204 | Shi Smith | Panthers | WR | South Carolina |
| 2021 | 6 | 227 | Israel Mukamu | Cowboys | CB | South Carolina |
| 2020 | 1 | 14 | Javon Kinlaw | 49ers | DT | South Carolina |
| 2020 | 3 | 81 | Bryan Edwards | Raiders | WR | South Carolina |
| 2020 | 4 | 117 | D.J. Wonnum | Vikings | DE | South Carolina |
| 2020 | 7 | 238 | TJ Brunson | Giants | LB | South Carolina |
| 2019 | 2 | 36 | Deebo Samuel | 49ers | WR | South Carolina |
| 2019 | 6 | 201 | Rashad Fenton | Chiefs | CB | South Carolina |
| 2019 | 6 | 212 | Dennis Daley | Panthers | OT | South Carolina |
| 2018 | 1 | 25 | Hayden Hurst | Ravens | TE | South Carolina |
| 2016 | 4 | 117 | Pharoh Cooper | Rams | WR | South Carolina |
| 2016 | 5 | 158 | Brandon Shell | Jets | OT | South Carolina |
| 2016 | 6 | 184 | Jerell Adams | Giants | TE | South Carolina |
| 2015 | 3 | 67 | A,J, Cann | Jaguars | OG | South Carolina |
| 2015 | 4 | 126 | Mike Davis | 49ers | RB | South Carolina |
| 2015 | 7 | 240 | Corey Robinson | Lions | OT | South Carolina |
| 2015 | 7 | 254 | Rory "Busta" Anderson | 49ers | TE | South Carolina |
| 2014 | 1 | 1 | Jadeveon Clowney | Texans | DE | South Carolina |
| 2014 | 4 | 106 | Bruce Ellington | 49ers | WR | South Carolina |
| 2013 | 2 | 57 | DJ Swearinger | Texans | S | South Carolina |
| 2013 | 4 | 101 | Ace Sanders | Jaguars | WR | South Carolina |
| 2013 | 4 | 131 | Marcus Lattimore | 49ers | RB | South Carolina |
| 2013 | 4 | 132 | Devin Taylor | Lions | DE | South Carolina |
| 2013 | 6 | 185 | DeVonte Holloman | Cowboys | LB | South Carolina |
| 2013 | 7 | 251 | T.J. Johnson | Bengals | C | South Carolina |
| 2013 | 7 | 254 | Justice Cunningham | Colts | TE | South Carolina |
| 2012 | 1 | 10 | Stephon Gilmore | Bills | CB | South Carolina |
| 2012 | 1 | 18 | Melvin Ingram | Chargers | DE | South Carolina |
| 2012 | 2 | 45 | Alshon Jeffery | Bears | WR | South Carolina |
| 2012 | 5 | 150 | Rokevious Watkins | Rams | OG | South Carolina |
| 2012 | 7 | 242 | Antonio Allen | Jets | S | South Carolina |
| 2012 | 7 | 249 | Travian Robertson | Falcons | DT | South Carolina |
| 2011 | 3 | 80 | Chris Culliver | 49ers | CB | South Carolina |
| 2010 | 4 | 124 | Eric Norwood | Panthers | LB | South Carolina |
| 2010 | 6 | 186 | Clifton Geathers | Browns | DE | South Carolina |
| 2009 | 3 | 89 | Jared Cook | Titans | TE | South Carolina |
| 2009 | 5 | 141 | Kenny McKinley | Broncos | WR | South Carolina |
| 2009 | 5 | 150 | Jasper Brinkley | Vikings | LB | South Carolina |
| 2009 | 5 | 162 | Jamon Meredith | Packers | OT | South Carolina |
| 2009 | 7 | 216 | Captain Munneryln | Panthers | CB | South Carolina |
| 2009 | 7 | 238 | Stoney Woodson | Giants | CB | South Carolina |
| 2009 | 7 | 256 | Ryan Succop | Chiefs | K | South Carolina |
| 2008 | 7 | 238 | Cory Boyd | Buccaneers | RB | South Carolina |
| 2007 | 2 | 44 | Sydney Rice | Vikings | WR | South Carolina |
| 2007 | 4 | 123 | Fred Bennett | Texans | CB | South Carolina |
| 2006 | 1 | 24 | Johnathan Joseph | Bengals | CB | South Carolina |
| 2006 | 4 | 105 | Ko Simpson | Bills | S | South Carolina |
| 2005 | 1 | 7 | Troy Williamson | Vikings | WR | South Carolina |
| 2005 | 7 | 220 | Rodriques Wilson | Bears | LB | South Carolina |
| 2005 | 7 | 241 | Darrell Shropshire | Falcons | DT | South Carolina |
| 2004 | 1 | 10 | Dunta Robertson | Texans | CB | South Carolina |
| 2004 | 3 | 94 | Travelle Wharton | Panthers | OT | South Carolina |
| 2004 | 6 | 184 | Deandre' Eiland | Vikings | S | South Carolina |
| 2003 | 6 | 174 | Langston Moore | Bengals | DT | South Carolina |
| 2003 | 7 | 229 | Andrew Pinnock | Chargers | FB | South Carolina |
| 2002 | 2 | 35 | Kalimba Edwards | Lions | DE | South Carolina |
| 2002 | 2 | 59 | Sheldon Brown | Eagles | CB | South Carolina |
| 2002 | 3 | 68 | Andre Goodman | Lions | CB | South Carolina |
| 2002 | 3 | 70 | Willie Offord | Vikings | S | South Carolina |
| 2002 | 6 | 193 | John Stamper | Buccaneers | DE | South Carolina |
| 2000 | 1 | 13 | John Abraham | Jets | LB | South Carolina |
| 2000 | 5 | 152 | Arturo Freeman | Dolphins | DB | South Carolina |
| 1998 | 5 | 130 | Darren Hambrick | Cowboys | LB | South Carolina |
| 1998 | 6 | 168 | Lee Wiggins | Oilers | DB | South Carolina |
| 1997 | 3 | 71 | Duce Staley | Eagles | RB | South Carolina |
| 1997 | 4 | 108 | Marcus Robinson | Bears | WR | South Carolina |
| 1996 | 4 | 118 | Stanley Pritchett | Dolphins | RB | South Carolina |
| 1996 | 5 | 137 | James Dexter | Cardinals | OT | South Carolina |
| 1994 | 3 | 98 | Corey Louchiey | Bills | OT | South Carolina |
| 1993 | 1 | 18 | Ernest Dye | Cardinals | OT | South Carolina |
| 1992 | 3 | 78 | Gerald Dixon | Browns | LB | South Carolina |
| 1992 | 9 | 225 | Eddie Miller | Colts | WR | South Carolina |
| 1991 | 3 | 56 | Calvin Stephens | Patriots | OG | South Carolina |
| 1991 | 6 | 167 | Corey Miller | Giants | LB | South Carolina |
| 1991 | 8 | 211 | Mike Dingle | Bengals | RB | South Carolina |
| 1991 | 12 | 324 | Ike Harris | Seahawks | OG | South Carolina |
| 1990 | 2 | 38 | Harold Green | Bengals | RB | South Carolina |
| 1990 | 9 | 247 | Todd Ellis | Broncos | QB | South Carolina |
| 1989 | 6 | 154 | Derrick Little | Buccaneers | LB | South Carolina |
| 1989 | 7 | 179 | Kevin Hendrix | Commanders | LB | South Carolina |
| 1988 | 1 | 7 | Sterling Sharpe | Packers | WR | South Carolina |
| 1988 | 2 | 54 | Brad Edwards | Vikings | DB | South Carolina |
| 1988 | 6 | 158 | Roy Hart | Seahawks | DT | South Carolina |
| 1988 | 11 | 296 | Norman Floyd | Vikings | DB | South Carolina |
| 1988 | 12 | 323 | Brendan McCormack | Giants | DT | South Carolina |
| 1987 | 10 | 259 | Raynard Brown | Lions | WR | South Carolina |
| 1986 | 3 | 77 | Leonard Burton | Bills | C | South Carolina |
| 1986 | 6 | 141 | Kent Hagood | Chiefs | RB | South Carolina |
| 1986 | 11 | 301 | Thomas Dendy | Broncos | RB | South Carolina |
| 1985 | 8 | 210 | Ira Hillary | Chiefs | WR | South Carolina |
| 1985 | 9 | 236 | Earl Johnson | Saints | DB | South Carolina |
| 1985 | 9 | 240 | Frank Wright | Giants | DT | South Carolina |
| 1985 | 11 | 282 | James Seawright | Bills | LB | South Carolina |
| 1984 | 3 | 60 | Rusty Russell | Eagles | OT | South Carolina |
| 1984 | 4 | 86 | Rickey Hagood | Seahawks | DT | South Carolina |
| 1983 | 3 | 75 | Andrew Provence | Falcons | DT | South Carolina |
| 1982 | 2 | 54 | Emanuel Weaver | Bengals | DT | South Carolina |
| 1982 | 6 | 160 | DeWayne Chivers | Bills | TE | South Carolina |
| 1982 | 8 | 198 | Chuck Slaughter | Saints | OT | South Carolina |
| 1982 | 12 | 307 | Johnnie Wright | Colts | RB | South Carolina |
| 1981 | 1 | 1 | George Rogers | Saints | RB | South Carolina |
| 1981 | 1 | 14 | Willie Scott | Chiefs | TE | South Carolina |
| 1980 | 11 | 285 | Steve Bernish | Giants | DE | South Carolina |
| 1979 | 1 | 25 | Rick Sanford | Patriots | DB | South Carolina |
| 1979 | 8 | 211 | Max Runager | Eagles | P | South Carolina |
| 1977 | 5 | 124 | Clarence Williams | Chargers | RB | South Carolina |
| 1977 | 5 | 125 | Steve Courson | Steelers | OG | South Carolina |
| 1977 | 7 | 195 | Kevin Long | Jets | RB | South Carolina |
| 1977 | 9 | 232 | Bill Currier | Oilers | DB | South Carolina |
| 1976 | 8 | 236 | Henry Laws | Cowboys | DB | South Carolina |
| 1976 | 11 | 317 | Brian Nemeth | Rams | TE | South Carolina |
| 1976 | 12 | 335 | Mike McCabe | Lions | C | South Carolina |
| 1976 | 17 | 480 | Jeff Grantz | Dolphins | QB | South Carolina |
| 1975 | 9 | 217 | Jay Hodgin | Packers | RB | South Carolina |
| 1974 | 7 | 159 | Marty Woolbright | Giants | TE | South Carolina |
| 1974 | 16 | 404 | Darrell Austin | Broncos | OT | South Carolina |
| 1973 | 7 | 169 | Mike Haggard | Jets | WR | South Carolina |
| 1973 | 9 | 230 | Rick Brown | Packers | LB | South Carolina |
| 1973 | 10 | 259 | John LeHeup | Bills | LB | South Carolina |
| 1973 | 15 | 374 | Jackie Brown | Colts | DB | South Carolina |
| 1972 | 5 | 114 | Dickie Harris | Jets | DB | South Carolina |
| 1972 | 5 | 126 | Bob Davies | Saints | DB | South Carolina |
| 1972 | 13 | 335 | Tyler Hellams | Chiefs | DB | South Carolina |
| 1971 | 11 | 279 | Jim Poston | Raiders | DT | South Carolina |
| 1971 | 15 | 370 | Dan Dyches | Jets | C | South Carolina |
| 1970 | 15 | 377 | Warren Muir | Giants | RB | South Carolina |
| 1969 | 14 | 352 | Roy Reeves | Oilers | DB | South Carolina |
| 1968 | 17 | 444 | Bob Cole | Steelers | LB | South Carolina |
| 1967 | 7 | 167 | Bob Bryant | Vikings | DB | South Carolina |
| 1967 | 12 | 294 | Stan Juk | Dolphins | LB | South Carolina |
| 1967 | 16 | 407 | Paul Phillips | Chargers | OT | South Carolina |
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